BDBM50475036 CHEMBL361462::TP-110
SMILES COc1ccc(CC(NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)Cc2cccc3ccccc23)C(C)C)C=O)cc1
InChI Key InChIKey=IJDYUMDIJFFMQQ-ROSKKCPQSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50475036
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration to inhibit the PGPH activity of 20S proteasome prepared from human leukemia HL-60 cells was determinedMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration to inhibit chymotrypsin-like activity of 20S proteasome prepared from human leukemia HL-60 cells was determinedMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Numazu Bio-Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration to inhibit trypsin-like activity of 20S proteasome from human leukemia HL-60 cells was determinedMore data for this Ligand-Target Pair